Tag: drug

• Rotatable Bonds & Drug Development

  

  Rotatable bonds are a critical factor in the design and development of drug molecules. In medicinal chemistry, the number of rotatable bonds in a molecule is an essential physicochemical property that affects its efficacy and pharmacokinetic properties. Rotatable bonds are single bonds that can freely rotate around their axis, which determines the molecule’s conformational flexibility.

  Max Schneider

  February 28, 2023

  Drug discovery

  biotech, Chemistry, drug