Tag: Cleavable linker
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Cleavable Vs. Non-Cleavable Linkers in ADCs

Antibody drug conjugates (ADCs) are a class of targeted cancer therapies that combine the specificity of monoclonal antibodies (mAbs) with the cytotoxic potency of small molecule drugs. These complex molecules consist of three components: the mAb, the cytotoxic drug, and the linker that connects them. The linker plays a critical role in ADCs as it…